Paraguay has a highly diverse climate, with major differences between regions. Annual temperatures range from lows of -14°C in the coldest regions to highs of 30°C in the warmest areas. Annual precipitation ranges from 93mm in drier regions to 393mm in wetter parts of the country. Some regions receive significant snowfall, with up to 349cm annually, while other areas see little to none. The warmest areas are hot year-round while the coldest regions remain very cold, making Paraguay a country of sharp climate contrasts.

Temperature patterns across Paraguay vary by region, with distinct differences between areas. The East is the warmest part of the country, with peak temperatures reaching 30°C and an annual average of 28°C. Cooler conditions are found in the South, where winter lows drop to -14°C and an annual average of -7°C. This 35°C difference in annual averages between regions means travellers can experience vastly different conditions depending on which part of Paraguay they visit. Regional temperature differences remain relatively consistent across seasons, with around 37°C of variation in both summer and winter. For example, Pedro Juan Caballero in the Departamento del Amambay averages 28°C annually, while Asunción in the Asunción averages -7°C.

Paraguay sees notable variation in rainfall across its regions, ranging from 93mm to 393mm per year. The North receives the most rainfall, at approximately 393mm annually. The Northeast is the driest, with around 93mm per year. Rainfall is distributed fairly evenly across the seasons, with no strong wet or dry period in most regions. The Northwest sees the most snowfall, with up to 349cm annually, while other parts of the country receive little to none. Travellers should pack rain gear when visiting wetter areas, while drier regions offer more favourable conditions throughout the year.